产品规格

1/5/25/50/100mg

抗体亚型

Rat IgG2a

推荐同型对照

InVivoMAb rat IgG2a isotype control,   anti-trinitrophenol（货号：BE0089）

推荐抗体稀释液

InVivoPure™ pH 7.0 Dilution Buffer（货号：IP0070）

免疫原

Recombinant mouse CD40 fusion protein

应用

in vivo CD40 activation

in vitro B cell stimulation/activation

产品形式

PBS, pH 7.0

Contains no stabilizers or preservatives

内毒素水平

<2EU/mg (<0.002EU/μg)

使用 LAL gel clotting 测定

纯度

>95% Determined by SDS-PAGE

无菌处理

0.2 μM filtered

生产形式

从组织培养上清液中纯化得到。

纯化形式

Protein G

RRID

AB_1107647

分子量大小

150 kDa

保存条件

抗体原溶液应保存在4°C条件下，不要冷冻保存。

in vivo CD40 activation

Bartkowiak, T., et al. (2015). “Unique potential of   4-1BB agonist antibody to promote durable regression of HPV+ tumors when   combined with an E6/E7 peptide vaccine.” Proc Natl Acad Sci U S A 112(38):   E5290-5299.

in vitro B cell stimulation/activation

Xu, H., et al. (2015). “Regulation of bifurcating B   cell trajectories by mutual antagonism between transcription factors IRF4 and   IRF8.” Nat Immunol.