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折扣/货期| 货号：701400 | 规格：96 wells | 目录价：￥6902 |
产品详情
产品名称:
PAD2 Inhibitor Screening Assay Kit (Ammonia)
别名:
PAD-H19|PADI2|Peptidylarginine Deiminase 2|Protein Arginine Deiminase 2
产品描述:
Protein Arginine Deiminase 2 (PAD2) is a guanidino-modifying enzyme that catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. This enzyme has been implicated in several diseases, including rheumatoid arthritis (RA), retinal degeneration, and certain cancers. PAD2 has been shown to modify vimentin, fibrinogen and β/γ-actin. Extracellular levels of PAD2 are increased in the lungs of smokers, providing a link between smoking as a risk factor for RA and anti-citrullinated protein antibodies among RA patients. Cayman's PAD2 Inhibitor Screening Assay (Ammonia) provides a convenient method for screening human PAD2 inhibitors.
保存温度:
-80
运输温度:
-80
有效期:
365
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