产品描述:
Gangliosesides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosesides has been linked to several diseases. Asialo-ganglioseside GM2 is a major neural ganglioseside in Tay Sachs and Sandhoff diseases.