官网链接
折扣/货期| 货号：CDX-P0063-M005 | 规格：5 mg | 目录价：￥1680 |
| 货号：CDX-P0063-M025 | 规格：25 mg | 目录价：￥6748 |
产品详情
产品名称:
PTACH
别名:
NCH 51; Cpd 51; S-[6-(4-Phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate
产品描述:
Non-hydroxamate HDAC inhibitor (HDACi) (IC50: 32, 48 and 41nM for HDAC4, HDAC1 and HDAC6, respectively). Cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor. Predicted to exhibit a similar HDAC binding mode as that of SAHA, interacting with the active-site zinc targeting group. Shown to exhibit comparable antiproliferative and apoptotic activity as SAHA against various cancer cell lines. Inhibits growth of various cancer cells in vitro (EC50 = 1.1 - 9.1µM). Also reactivates latent HIV-1 gene expression.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
390.56
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
848354-66-5
分子式:
C20H26N2O2S2
溶解度:
Soluble in DMSO (25mg/ml).
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