货号:350-09-100ug | 规格:100ug | 目录价:¥11600 |
货号:350-09-1mg | 规格:1mg | 目录价:¥51397 |
货号:350-09-250ug | 规格:250ug | 目录价:¥22431 |
货号:350-09-25ug | 规格:25ug | 目录价:¥2910 |
货号:350-09-500ug | 规格:500ug | 目录价:¥33338 |
货号:350-09-50ug | 规格:50ug | 目录价:¥7870 |
货号:350-09-5ug | 规格:5ug | 目录价:¥1169 |
产品详情
产品名称:
Recombinant Human IGF-BP7
别名:
Insulin-like Growth Factor-Binding Protein 7, IBP-7, Mac25, IGF binding protein related protein-1 (IGFBP-rP1)
产品描述:
IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues, and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF-induced differentiation of skeletal myoblasts, without affecting IGF-induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF-independent mechanism, which causes a delay in the G1 phase of the cell cycle and increased apoptosis. Recombinant Human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
26.4 kDa
产品形式:
Bulk
产地:
美国
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