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折扣/货期| 货号：SBB-UP0013-M010 | 规格：10 mg | 目录价：￥1638 |
产品详情
产品名称:
Ubiquitin (human) (rec.) (untagged)
别名:
UBB; Ubiquitin B
产品描述:
Ubiquitin is a 76 amino acid post-translational modifier expressed throughout all tissues in eukaryotic organisms. The many roles of ubiquitin modification include proteasomal degradation, signal transduction, inflammatory response and DNA damage repair. Ubiquitin modification occurs through a pyramidal cascade of an E1 activating enzyme, E2 conjugating enzymes and an E3 ubiquitin ligase. This enzymatic cascade results in modification of a epsilon-amine of a lysine residue on a substrate protein. Substrates may either be mono- or poly-ubiquitinated by M1, K6, 11, 27, 29, 33, 48 or 63 linkages. Removal of ubiquitin from a substrate protein occurs via deconjugating enzymes, of which there are nearly 100 known enzymes with various specificities.
宿主来源:
E. coli
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~9kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>99% (SDS-PAGE)
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