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    Ubiquitin-AMC (human) (rec.) (untagged)
    品牌:Adipogen
    货号:SBB-PS0043-C050 规格:50 ug 目录价:¥3304
    产品详情
    产品名称:
    Ubiquitin-AMC (human) (rec.) (untagged)
    别名:
    Ub-AMC; Ub-7-Amido-4-methylcoumarin
    产品描述:
    Ubiquitin is a 76 amino acid post-translational modifier expressed throughout all tissues in eukaryotic organisms. The many roles of ubiquitin modification include proteasomal degradation, signal transduction, inflammatory response, and DNA damage repair. Ubiquitin modification occurs through a pyramidal cascade of an E1 activating enzyme, E2 conjugating enzymes, and an E3 ubiquitin ligases. This enzymatic cascade results in modification of a epsilon-amine of a lysine residue on a substrate protein. Substrates may either be mono or poly-ubiquitinated by M1, K6, 11, 27, 29, 33, 48 or 63 linkages. Removal of ubiquitin from a substrate protein occurs via deconjugating enzymes, of which there are nearly 100 known enzymes with various specificities.
    宿主来源:
    E. coli
    偶联:
    AMC
    产品浓度:
    Lot dependent.
    保存温度:
    -80°C
    运输温度:
    Dry Ice
    预期分子量:
    ~8.7kDa
    产品形式:
    liquid
    存储溶液:
    Liquid. In 50mM MES pH 6.0.
    有效期:
    Stable for at least 1 year after receipt when stored at -80°C.
    产地:
    瑞士
    纯度:
    >99% (LCMS)
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