近期,中国科学院上海药物研究所于海军老师课题组在国际权威学术期刊Advanced materials上发表了题为“Engineering Stimuli-Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy”的论文,本文首次报道了一种用于免疫调节剂(如免疫激活剂和免疫抑制剂)的肿瘤靶向协同输送及联合免疫治疗的布尔逻辑前药纳米粒(BLPNs)。构建了一个刺激激活BLPNs库,通过调整输入组合包括肿瘤微环境中的细胞外基质金属蛋白2/9(MMP-2/9)、细胞内酸度(pH=5.0-6.0)和还原型谷胱甘肽,来产生YES/AND逻辑输出。通过指定正交刺激-不稳定部分的分子结构和连接性,同时利用肿瘤部位内源性信号,实现对BLPNs分解和前药活化的选择性可调控制,进一步证明了BLPNs在肿瘤中的特异性分布和高效肿瘤免疫治疗中免疫调节剂的刺激激活作用。本研究结果为肿瘤药物特异性输送和精准的癌症免疫治疗开辟了新的途径。
本研究使用欣博盛IL-6, TNF-ɑ和IFN-γ ELISA试剂盒检测了小鼠肿瘤组织样本中的细胞因子的含量。
文章影响因子:25.809
文章链接:https://www.ncbi.nlm.nih.gov/pubmed/32048361
以下是2020年4月欣博盛品牌产品SCI文献引用文章汇总
1.文章题目:Aging-induced IL27Ra Signaling Impairs Hematopoietic Stem Cells.
期 刊:Blood(影响因子:16.562)
发表时间:17 April 2020
作 者:He H, Xu P, Zhang X, et al.
作者单位:清华大学
使用产品:Mouse TNF-α ELISA Kit
https://www.ncbi.nlm.nih.gov/pubmed/32305041
2.文章题目:Dipeptide Self-Assembled Hydrogels with Shear-Thinning and Instantaneously Self-Healing Properties Determined by Peptide Sequences.
期 刊:ACS Applied Materials & Interfaces(影响因子:8.456)
发表时间:22 April 2020
作 者:Ren P, Li J, Zhao L, et al.
作者单位:中国科学院过程工程研究所
使用产品:Mouse IL-6, IL-10, TNF-α, TGF-β1 ELISA Kits
样本类型:皮肤组织
https://www.ncbi.nlm.nih.gov/pubmed/32319760
3.文章题目:Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury.
期 刊:Cell Death & Disease(影响因子:5.959)
发表时间:17 April 2020
作 者:Li J, Zhao J, Xu M, et al.
作者单位:上海交通大学医学院仁济医院
使用产品:Mouse IL-6, TNF-α and IL-1β ELISA Kits
https://www.ncbi.nlm.nih.gov/pubmed/32303674
4.文章题目:Dual modulation of formyl peptide receptor 2 by aspirin-triggered lipoxin contributes to its anti-inflammatory activity.
期 刊:The FASEB Journal(影响因子:5.391)
发表时间:02 April 2020
作 者:Ge Y, Zhang S, Wang J, et al.
作者单位:澳门大学
使用产品:Human IL-8 ELISA Kit
https://www.ncbi.nlm.nih.gov/pubmed/32239559
5.文章题目:B7-H3 inhibits the IFN-γ-dependent cytotoxicity of Vγ9Vδ2 T cells against colon cancer cells.
期 刊:OncoImmunology(影响因子:5.333)
发表时间:14 April 2020
作 者:Lu H, Shi T, Wang M, et al.
作者单位:苏州大学第一附属医院
使用产品:Human IFN-γ, IL-17/IL-17A, IL-4 and TNF-α ELISA Kits
https://www.tandfonline.com/doi/full/10.1080/2162402X.2020.1748991
6.文章题目:Changes in colonic microbiotas in rat after long-term exposure to low dose of okadaic acid.
期 刊:Chemosphere(影响因子:5.108)
发表时间:25 April 2020
作 者:Liu Y, Zheng J W, Peng X C, et al.
作者单位:暨南大学
使用产品:Rat TNF-α, IL-6, IL-8 and IL-10 ELISA Kits
https://www.sciencedirect.com/science/article/pii/S0045653520310675
7.文章题目:Tricarabrols AC, three anti-inflammatory sesquiterpene lactone trimers featuring methylene-tethered linkage from Carpesium faberi.
期 刊:Organic Chemistry Frontiers(影响因子:5.076)
发表时间:22 April 2020
作 者:Yuan J, Wen X, Ke C Q, et al.
作者单位:中国科学院上海药物研究所
使用产品:Mouse TNF-α, IL-6 and MCP-1 ELISA Kits
https://pubs.rsc.org/en/content/articlelanding/2020/qo/d0qo00093k#!divAbstract
8.文章题目:Combined blockade of TGf-β1 and GM-CSF improves chemotherapeutic effects for pancreatic cancer by modulating tumor microenvironment.
期 刊:Cancer Immunology, Immunotherapy(影响因子:4.9)
发表时间:13 April 2020
作 者:Liu Q, Wu H, Li Y, et al.
作者单位:北京协和医学院
使用产品:Annexin V-FITC/PI apoptosis assay kit
https://www.ncbi.nlm.nih.gov/pubmed/32285172
9.文章题目:Immunization With a Secreted Esterase Protects Mice Against Multiple Serotypes (M1, M3, and M28) of Group A Streptococcus.
期 刊:Frontiers in Microbiology(影响因子:4.259)
发表时间:03 April 2020
作 者:Zhang X, Wei D, Zhao Y, et al.
作者单位:哈尔滨医科大学
使用产品:Mouse IgG ELISA Kit
https://www.frontiersin.org/articles/10.3389/fmicb.2020.00565/full
10.文章题目:Nevirapine Increases Sodium/Iodide Symporter-Mediated Radioiodide Uptake by Activation of TSHR/cAMP/CREB/PAX8 Signaling Pathway in Dedifferentiated Thyroid Cancer.
期 刊:Frontiers in Oncology(影响因子:4.137)
发表时间:April 2020
作 者:Shang H, Zhao J, Yao J, et al.
作者单位:山东大学附属千佛山医院
使用产品:Annexin V-FITC/PI apoptosis assay kit
https://www.ncbi.nlm.nih.gov/pubmed/32300552
11.文章题目:Cryptotanshinone protects dextran sulfate sodium-induced experimental ulcerative colitis in mice by inhibiting intestinal inflammation.
期 刊:Phytotherapy Research(影响因子:3.766)
发表时间:17 April 2020
作 者:Min X, Zeng X, Zhao W, et al.
作者单位:遵义医科大学
使用产品:Mouse TNF-α, IL-1β and IL-6 ELISA Kits
样本类型:结肠组织
https://www.ncbi.nlm.nih.gov/pubmed/32302031
12.文章题目:Probiotic Enterococcus faecalis Symbioflor 1 ameliorates pathobiont-induced miscarriage through bacterial antagonism and Th1-Th2 modulation in pregnant mice.
期 刊:Applied Microbiology and Biotechnology(影响因子:3.67)
发表时间:20 April 2020
作 者:Tao Y, Huang F, Zhang Z, et al.
作者单位:南昌大学
使用产品:Mouse TNF-α, IFN-α and IL-10 ELISA Kits
https://www.ncbi.nlm.nih.gov/pubmed/32314005
13.文章题目:Comparative study of intratracheal and oral gefitinib for the treatment of primary lung cancer.
期 刊:European Journal of Pharmaceutical Sciences(影响因子:3.532)
发表时间:18 April 2020
作 者:Zhang T, Wang R, Li M, et al.
作者单位:中国医学科学院放射医学研究所
使用产品:Rat TNF-α ELISA Kit
样本类型:支气管肺泡灌洗液
https://www.sciencedirect.com/science/article/abs/pii/S092809872030141X
14.文章题目:Natural phenylethanoid glycosides isolated from Callicarpa kwangtungensis suppressed lipopolysaccharide-mediated inflammatory response via activating Keap1/Nrf2/HO-1 pathway in RAW 264.7 macrophages cell.
期 刊:Journal of Ethnopharmacology(影响因子:3.414)
发表时间:13 April 2020
作 者:Wu A, Yang Z, Huang Y, et al.
作者单位:广州中医药大学
使用产品:Mouse TNF-α and IL-6 ELISA Kits
https://www.sciencedirect.com/science/article/abs/pii/S0378874119349177
15.文章题目:Phorbol myristate acetate induces cellular senescence in rat microglia in vitro.
期 刊:International Journal of Molecular Medicine(影响因子:2.928)
发表时间:23 April 2020
作 者:Cao D, Li X H, Luo X G, et al.
作者单位:沈阳市第四人民医院
使用产品:Annexin V-FITC/PI apoptosis assay kit
https://www.spandidos-publications.com/10.3892/ijmm.2020.4587
16.文章题目:Pithecellobium clypearia extract enriched in gallic acid and luteolin has antibacterial activity against MRSA and reduces resistance to erythromycin, ceftriaxone sodium and levofloxacin.
期 刊:Journal of Applied Microbiology(影响因子:2.683)
发表时间:17 April 2020
作 者:Liu C, Huang H, Zhou Q, et al.
作者单位:中山大学
使用产品:Mouse TNF-α, IL-6 and IL-8 ELISA Kits
样本类型:支气管肺泡灌洗液
https://www.ncbi.nlm.nih.gov/pubmed/32301544
17.文章题目:Oral immunization of BALB/c mice with recombinant Helicobacter pylori antigens and double mutant heat-labile toxin (dmLT) induces prophylactic protective immunity against H. pylori infection.
期 刊:Microbial Pathogenesis(影响因子:2.581)
发表时间:27 April 2020
作 者:Zhong Y, Chen J, Liu Y, et al.
作者单位:北京生物制品研究所
使用产品:Mouse IL-17, IL-16, IL-6 and TNF-α ELISA Kits
https://www.sciencedirect.com/science/article/abs/pii/S0882401020305167
18.文章题目:IP10, KC and M-CSF is Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents.
期 刊:Virologica Sinica(影响因子:2.467)
发表时间:20 April 2020
作 者:Chen J, Chen C, Hu C, et al.
作者单位:黑龙江八一农垦大学
使用产品:Mouse IP-10, KC, M-CSF and human IP-10 ELISA Kits
样本类型:小鼠大脑组织和人脑脊液
https://www.ncbi.nlm.nih.gov/pubmed/32314275
19.文章题目:Exosomes derived from M0, M1 and M2 macrophages exert distinct influences on the proliferation and differentiation of mesenchymal stem cells.
期 刊:PeerJ(影响因子:2.353)
发表时间:24 April 2020
作 者:Xia Y, He X T, Xu X Y, et al.
作者单位:第四军医大学
使用产品:Mouse TNF-α and IL-10 ELISA Kits
https://peerj.com/articles/8970.pdf
20.文章题目:High Glucose Induces the Loss of Retinal Pericytes Partly via NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis.
期 刊:BioMed Research International(影响因子:2.197)
发表时间:27 April 2020
作 者:Gan J, Huang M, Lan G, et al.
作者单位:西南医科大学附属医院
使用产品:Human IL-1β and IL-18 ELISA Kits
https://www.hindawi.com/journals/bmri/2020/4510628/
21.文章题目:Wasp Venom Possesses Potential Therapeutic Effect in Experimental Models of Rheumatoid Arthritis.
期 刊:Evidence-Based Complementary and Alternative Medicine(影响因子:1.984)
发表时间:06 April 2020
作 者:Gao Y, Yu W X, Duan X M, et al.
作者单位:大理大学
使用产品:Rat IgA, IgG and IgM ELISA Kits
https://www.hindawi.com/journals/ecam/2020/6394625/
22.文章题目:Cytochrome P450 Epoxygenase 2J2 Protects Against Lung Ischemia/Reperfusion Injury by Activating the P13K/Akt/GSK-3-β/NF-kB Signaling Pathway During Deep Hypothermic Low Flow in Mice.
期 刊:Journal of Surgical Research(影响因子:1.872)
发表时间:16 April 2020
作 者:Yang Y, Wang J, Peng W, et al.
作者单位:南京医科大学附属儿童医院
使用产品:Mouse IL-1β, IL-6, IL-8, IL-10 and TNF-α ELISA Kits
https://www.sciencedirect.com/science/article/pii/S0022480420300470
23.文章题目:Increased p300/CBP expression in acute respiratory distress syndrome is associated with interleukin-17 and prognosis.
期 刊:The Clinical Respiratory Journal(影响因子:1.751)
发表时间:16 April 2020
作 者:Chen Y, Huang B, Zhao Y, et al.
作者单位:重庆医科大学附属第二医院
使用产品:Human IL-17, IL-6 and IL-10 ELISA Kits
https://www.ncbi.nlm.nih.gov/pubmed/32298537
24.文章题目:Bioactivity-guided isolation of anti-inflammatory components from Phyllanthus emblica.
期 刊:Food Science & Nutrition(影响因子:1.747)
发表时间:22 April 2020
作 者:Li W, Zhu H, Chen Y, et al.
作者单位:华南农业大学
使用产品:Mouse IL-1β, IL-6, and TNF-α ELISA Kits
https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.1553
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