货号:38568 | 规格:2.7 mg | 目录价:¥2282 |
产品详情
产品名称:
2'-O-Methylguanosine-5'-O-triphosphate (sodium salt)
别名:
2'-methyl GTP|2'-O-methyl GTP
产品描述:
2'-O-Methylguanosine-5'-O-triphosphate (2’-methyl GTP) is an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50 = 3.5 µM) and an active metabolite of the prodrug IDX184.{67400,67401} It is formed from IDX184 via a 2’-methylguanosine (Item No. 21039) intermediate.{67401} 2’-methyl GTP (50 µM) also induces tubulin polymerization.{67402} Tumoral levels of 2’-methyl GTP are decreased in patients with hepatocellular carcinoma compared with adjacent normal tissue.{67403}
保存温度:
-80
运输温度:
-80
预期分子量:
625.1
产品形式:
A solution in water
有效期:
730
纯度:
≥95%
分子式:
C11H14N5O14P3 • 4Na
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