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折扣/货期| 货号：40644-1 g | 规格：1 g | 目录价：￥770 |
| 货号：40644 | 规格：500 mg | 目录价：￥406 |
产品详情
产品名称:
5-Bromo-2'-deoxycytidine
别名:
5-Bromodeoxycytidine|BrdC|BrdCyd|NSC 61765
产品描述:
5-Bromo-2'-deoxycytidine (BrdC) is a brominated derivative of the deoxyribonucleoside 2’-deoxycytidine (Item No. 34708).{67704} It induces DNA cross-linking and the formation of DNA strand breaks when incorporated into a DNA fragment in place of cytosine and exposed to UVB damage.{67705} BrdC inhibits cytopathogenicity induced by herpes simplex virus 1 (HSV-1) and HSV-2 in infected primary rabbit kidney (PRK) cells (MICs = 0.2-0.3 µg/ml).{36599} It decreases survival of U-1 melanoma cells and AG1522 non-cancerous cells and induces sensitization of both to radiation.{67704} BrdC also sensitizes tumors to radiation and reduces tumor volume in a mouse model of glioma using RT-2 cells infused with an adenovirus expressing HSV thymidine kinase (ADV-TK) after implantation.{67706} In vivo, BrdC is converted to 5-bromo-2'-deoxyuridine (BrdU; Item No. 15580) and has been used to label cardiac progenitor cells (CPCs) in a rat model of myocardial infarction.{67707}
保存温度:
-20
运输温度:
-20
预期分子量:
306.1
产品形式:
A solid
有效期:
1460
纯度:
≥95%
CAS号:
1022-79-3
分子式:
C9H12BrN3O4
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