货号:GTX84981 | 规格:100μg | 目录价:¥6400 |
产品详情
产品名称:
Bim antibody [1C2C8]
别名:
BCL2 like 11 , BAM , BIM , BOD
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, WB
同种型:
IgG1
免疫原:
Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
克隆性:
Monoclonal
克隆号:
1C2C8
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
阳性对照:
K-562 Cell Slide(GTX25535) , Bim Recombinant Protein
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
22
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
产地:
美国
功能与背景:
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
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