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折扣/货期| 货号：GTX639925-S | 规格：100μl | 目录价：￥3300 |
| 货号：GTX639925 | 规格：500μl | 目录价：￥6500 |
产品详情
产品名称:
PD-L1 antibody [H302] HistoMAX™
别名:
CD274 molecule,B7-H,B7H1,PD-L1,PDCD1L1,PDCD1LG1,PDL1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
This antibody was raised against human PD-L1 Intracellular domain, and it does not cross with PD-L2 protein.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Intracellular domain of human PD-L1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
H302
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 2% BSA, 0.025% ProClin 300.
产地:
美国
功能与背景:
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
产品特点:
HistoMAX, Recombinant antibody
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