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折扣/货期| 货号：CHI-MF-12002-C010 | 规格：10 ug | 目录价：￥2940 |
| 货号：CHI-MF-12002-C050 | 规格：50 ug | 目录价：￥5040 |
产品详情
产品名称:
IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)
别名:
Interleukin-2; Aldesleukin
产品描述:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
宿主来源:
NS1 cells
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~46kDa (monomer)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Specific Activity: 1-1.5 x106 Units/mg, measured using CTLL indicator cells. Shows the biological function of the IL-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Blocks diabetogenic autoimmunity in nonobese diabetic mice.
内毒素水平:
<0.06EU/µg protein (LAL test; Lonza).
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