官网链接
折扣/货期| 货号：CHI-MF-12021-C050 | 规格：50 ug | 目录价：￥5600 |
产品详情
产品名称:
IL-21 (mouse):Fc (mouse) (rec.) (non-lytic)
别名:
Interleukin-21
产品描述:
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays a supportive role in the proliferation of T and B cells and influences the cytolytic activity of natural killer cells. IL-21 has been shown to up-regulate genes associated with innate immunity and to inhibit the differentiation of naïve T helper cells. IL-21 specifically inhibits IFN-gamma production from developing TH1 cells and is preferentially expressed by TH2 cells. Furthermore IL-21 has been identified as a growth and survival factor for human myeloma cells. IL-21/IL-21R interactions have a unique role in sequentially activating both innate and adaptive immune responses against poorly immunogenic tumors, leading to tumor rejection that is perforin dependent but IFN-gamma independent.
宿主来源:
CHO cells
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~40-50kDa
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Shows the biological function of the IL-21 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
内毒素水平:
<1EU/mg protein (LAL test; Lonza).
您可能感兴趣的产品
Human IL1F5 protein, His tag
货号：GTX68383-pro
Human VEGF165 protein, His tag
货号：GTX67937-pro
Rat IL6 protein, His tag (active)
货号：GTX67073-pro
Human IL6 protein, His tag (active)
货号：GTX67071-pro
Human IL2 protein (active)
货号：GTX67060-pro
Feline IL2 protein, His tag (active)
货号：GTX66898-pro
Human IL1 Receptor 1 protein, human IgG1 Fc tag (active)
货号：GTX65662-pro
Human IL1F10 protein, His tag
货号：GTX57238-pro
促销活动
精品推荐
相关产品推荐
IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12002-C010
IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12004-C010
IL-6 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12006-C050
IL-10 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12010-C010
IL-21R (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12021R-C025
IL-4 (mouse) (rec.) (His)
货号：CHI-MR-10004-C010
