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折扣/货期| 货号：38491 | 规格：2.5 mg | 目录价：￥3556 |
产品详情
产品名称:
Purine riboside-5'-O-triphosphate (sodium salt)
别名:
PRTP|PTP|Purine Riboside Triphosphate|PuTP
产品描述:
Purine riboside-5'-O-triphosphate (PRTP) is an active metabolite of the antiviral, antibacterial, and anticancer agent nebularine (Item No. 31329).{69371} It is formed from nebularine by adenosine kinase, which results in depletion of intracellular ATP levels and induces cell death in isolated rat thymocytes, an effect that can be reduced by the adenosine kinase inhibitor 5-iodotubercidin (Item No. 10010375). PRTP is an inhibitor of DNA primase ATP and GTP polymerization activities (IC50s = 35 and 28 µM, respectively, for the human enzyme) and of calmodulin-dependent protein kinase II (CaMKII; Ki = 590 µM).{69372,69373}
保存温度:
-80
运输温度:
-80
预期分子量:
580.1
产品形式:
A solution in water
有效期:
730
纯度:
≥95%
来源:
Synthetic
CAS号:
35892-95-6
分子式:
C10H11N4O13P3 • 4Na
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