货号:CDX-T0072-M250 | 规格:250 mg | 目录价:¥5138 |
产品详情
产品名称:
Temozolomide
别名:
3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide; CCRG 81045; MB 39831; Methazolastone; NSC 362856; Temodal
产品描述:
Temozolomide is a DNA methylating agent and drug resistance-modifying agent with antitumor and antiangiogenic properties. Temozolomide induces G2/M arrest and apoptosis through adduction of a methyl group to O6 position of guanine in genomic DNA and interfering with DNA replication and leading to cytotoxicity in proliferating cells. It has been shown to induce autophagy in malignant glioma cells. It is effective in a variety of types of cancer, including aggressive brain cancers.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
194.15
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at +4°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
85622-93-1
分子式:
C6H6N6O2
溶解度:
Soluble in DMSO (5mg/ml) or DMF (5mg/ml).
促销活动
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