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折扣/货期| 货号：CDX-U0400-M500 | 规格：500 mg | 目录价：￥1778 |
产品详情
产品名称:
Ursolic acid
别名:
3beta-Hydroxy-12-ursen-28-oic acid; Bungeolic Acid; Maerotaine; Malol; NSC 4060; NSC 167406
产品描述:
Ursolic acid is a pentacyclic triterpenoid that has been isolated from M. pumila. Ursolic acid has diverse biological effects, including anti-inflammatory, anticancer, antidiabetic, antiobesity, neuroprotective, cardioprotective, hepatoprotective, antioxidant and antiviral and antibacterial effects. Effects relevant to its anticancer properties include, apoptosis and autophagy induction, preventing angiogenesis, microtubule-destabilizing, induction of cell cycle arrest and inhibition of tumor growth. Ursolic acid inhibits NF-kappa signaling through suppression of IkappaBalpha kinase and p65 phosphorylation. It has been shown to enhance pancreatic beta-cell function in diabetic mice and activates the TGR5 receptor to enhance GLP-1 secretion. Its antiobesity potential is related to inhibiting pancreatic lipase and adipogenesis and increasing insulin sensitivity and inhibiting alpha-glucosidase. Ursolic acid is also liver X receptor alpha (LXRalpha) antagonist inhibiting ligand-induced Nnnalcoholic fatty liver and drug-induced lipogenesis. Ursolic acid also scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and inhibits the growth of several strains of Gram-positive and Gram-negative bacteria in vitro.
宿主来源:
Plant
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
456.711
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
77-52-1
分子式:
C30H48O3
溶解度:
Soluble in DMSO (10mg/ml) or DMF (10mg/ml).
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