P物质是一种十一肽激素（RPKPQQFFGLM），是神经肽速激肽家族的一员，可介导多种生物活动，参与感觉、运动、情绪等的调节，并与焦虑症、抑郁症、精神分裂症的发病机理有关。P物质广泛分布于脊椎动物的外周和中枢神经系统，在负责调节情绪的脑区（杏仁核、导水管周围灰质和下丘脑等）比较丰富，同时在初级感觉神经元的胞体及神经纤维上有较高表达。
ENZO P物质ELISA试剂盒是一种比色竞争法免疫测定试剂盒，用低样本量即可检测38个带复孔样本，3小时内即可获得结果。该试剂盒在405 nm处读取吸光度。
● 高灵敏度，可检测低至5.3 pg/ml的P物质
● 广泛的文献引用
● 高通量，可检测多达38个样本（带复孔）
● 超越半定量蛋白质印迹分析的全定量检测
产品信息
| 产品货号 | ADI-900-018A/ ADI-901-018A |
产品名称 | Substance P ELISA kit（P物质ELISA试剂盒） |
规格 | 96 wells/ 5x96 wells |
灵敏度 | 5.3 pg/ml |
检测范围 | 9.76 - 10,000 pg/ml |
检测时间 | 3 hours |
样本种属 | Species independent |
样本类型 | culture supernatants, plasma, serum, saliva, and urine. Cited sample type includes tissue. |
保存温度 | Store components at temperatures indicated on the component labeling. |
试剂盒组分 | GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution |
部分产品引用文献
1. A Potential Role for Substance P in West Nile Virus Neuropathogenesis: S.E. Ronca, et al.; Viruses 14, 1961 (2022)
2. Elevated serum substance P during simian varicella virus infection in rhesus macaques: implications for chronic inflammation and adverse cerebrovascular events: A. Bubak, et al.; J. Neurovirol. 26, 945 (2020)
3. Role of the afferent renal nerves in sodium homeostasis and blood pressure regulation in rats: A.A. Frame, et al.; Exp. Physiol. 104, 1306 (2019), Application(s): ELISA using culture supernatants
4. Sensory neuropeptides and their receptors participate in mechano-regulation of murine macrophages: D. Muschter, et al.; Int. J. Mol. Sci. 20, 503 (2019), Application(s): ELISA using culture supernatants
5. Aggressive attempted escape behavior during head-lock restraint reduced reproductive performances in Holstein heifers: V.R. Kasimanickam, et al.; Theriogenology 121, 147 (2018), Application(s): ELISA using bovine serum
6. Effects of castration and a lidocaine-plus-flunixin treatment on growth and indicators of pain, inflammation, and liver function in Korean cattle bull calves: S.J. Park, et al.; Livestock Sci. 216, 61 (2018), Application(s): Bovine Plasma
7. Predictors of beef calf temperament at weaning and its impact on temperament at breeding and reproductive performance: V.R. Kasimanickam, et al.; Reprod. Domest. Anim. 53, 484 (2018), Application(s): ELISA using bovine serum
8. Saliva as a medium to detect and measure biomarkers related to pain: H. Jasim, et al.; Sci. Rep. 8, 3220 (2018), Application(s): ELISA using human plasma and saliva
9. Effects on breathing of agonists to μ-opioid or GABAA receptors dialyzed into the Ventral Respiratory Column of awake and sleeping goats: T.M. Langer, et al.; Respir. Physiol. Neurobiol. 239, 10 (2017)
10. Flunixin meglumine improves pregnancy rate in embryo recipient beef cows with an excitable temperament: R.K. Kasimanickam, et al.; Theriogenology 107, 70 (2017)
11. Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice: L.R. Reznikov, et al.; PLoS One 11, e0166089 (2016)
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