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折扣/货期| 货号：GTX01507 | 规格：1mg | 目录价：￥1200 |
产品详情
产品名称:
Peanut Lectin (Biotin)
别名:
Peanut Lectin , PNA , PNA lectin , Arachis hypogaea , Arachis hypogaea lectin , Peanut agglutinin lectin , Peanut agglutinin
产品描述:
Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosesides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells.
实验应用:
ELISA, IHC, WB
靶标/特异性:
Carbohydrate-Binding Specificity of Peanut Lectin : Galβ1, 3 GalNAc>>GalNAc>Gal
克隆号:
纯化方式:
Purified by affinity chromatography followed by gel filtration chromatography
偶联:
Biotin
产品浓度:
5 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
Native Protein
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM Bicarbonate, 150mM NaCl, 0.1mM CaCl₂. Dilute in PBS, 0.1mM CaCl₂, 0.05% Sodium azide.
产地:
美国
功能与背景:
Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosesides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells. Peanut lectin contains one atom of Ca++ and Mg++ per unit.
Inhibiting/Eluting sugars: 200 mM Galactose
Carbohydrate-Binding Specificity of PNA: Galβ1, 3 GalNAc>>>>>GalNAc>Gal
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