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Recombinant Human HVEM-Fc
品牌:PeproTech
货号:310-27-200 规格:200ug 目录价:¥7052
货号:310-27-500 规格:500ug 目录价:¥12223
货号:310-27-100ug 规格:100ug 目录价:¥2850
货号:310-27-1mg 规格:1mg 目录价:¥18849
货号:310-27-20ug 规格:20ug 目录价:¥1169
产品详情
产品名称:
Recombinant Human HVEM-Fc
别名:
HVEM, TNFSFR14, ATAR, TR2
产品描述:
HVEM belongs to the TNF Receptor superfamily of transmembrane proteins, and plays a role in the activation of T-cells and other lymphocytes. It is expressed in various cells and tissues, including spleen, thymus, lung, macrophages, and T-cells. HVEM activation induces a signaling cascade that results in the induction of transcription factors NF-kappaB and AP-1. LIGHT (TNFSF14) and TNF-beta (TNFSF1) function as the ligands for HVEM, which can also bind specifically to herpes simplex virus glycoprotein D. Soluble HVEM, which tends to form disulfide-linked heterodimeric complexes in solution, can act as a "receptor decoy" resulting in inhibition of the activity of the HVEM ligands, LIGHT and TNF-beta. Recombinant Human HVEM-Fc Chimera is a 376 amino acid fusion protein that contains an N-terminal domain corresponding to the extracellular region of HVEM, and a C-terminal domain corresponding to residues 102 to 330 of human IgG1. The calculated molecular weight of Recombinant Human HVEM-Fc is 41.4 kDa.
宿主来源:
Hi-5 Insect cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
41.4 kDa
产品形式:
Standard
产地:
美国
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