官网链接
折扣/货期| 货号：450-42-100ug | 规格：100ug | 目录价：￥5760 |
| 货号：450-42-10ug | 规格：10ug | 目录价：￥1163 |
| 货号：450-42-1mg | 规格：1mg | 目录价：￥25574 |
| 货号：450-42-250ug | 规格：250ug | 目录价：￥11161 |
| 货号：450-42-500ug | 规格：500ug | 目录价：￥16583 |
| 货号：450-42-50ug | 规格：50ug | 目录价：￥2900 |
产品详情
产品名称:
Recombinant Human sCD30 Ligand
别名:
soluble CD30 Ligand, TNFSF8, CD153, CD30L
产品描述:
CD30 ligand (CD30L) is a type-II membrane-associated glycoprotein belonging to the TNF superfamily and is expressed primarily on certain B cells, T cells, and monocytes. CD30L binds specifically to CD30 (receptor), which is expressed on activated, but not resting, B and T cells, in lymphomas and various chronically inflamed tissues. CD30L/CD30 interactions initiate a signaling cascade that can ultimately lead to the activation of NF-kappaB. CD30L/CD30 signaling exerts pleiotropic effects on normal cells, including cell death, differentiation, and cell division. Certain diseases, including Hodgkin's lymphoma, allergic inflammation, diabetes (in NOD mice), and mycobacterial infection can also be affected by CD30L/CD30 signaling. The CD30L gene encodes for a 234 amino acid type II transmembrane protein, which contains a 37 amino acid cytoplasmic sequence, a 25 amino acid transmembrane domain and a 172 amino acid extracellular domain. Recombinant Human soluble CD30L (sCD30L) is a 188 amino acid polypeptide corresponding to the extracellular domain, and contains an 8 residue N-terminal His-Tag. The calculated molecular weight of Recombinant Human sCD30L is 21.3 kDa.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
21.3 kDa
产品形式:
Standard
产地:
美国
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