Recombinant Human sOX40 Ligand-其他重组蛋白-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳爱游戏ayx(中国)官方网站有限公司

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Recombinant Human sOX40 Ligand

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：310-28-100ug	规格：100ug	目录价：￥22138
货号：310-28-10ug	规格：10ug	目录价：￥2836
货号：310-28-1mg	规格：1mg	目录价：￥88652
货号：310-28-250ug	规格：250ug	目录价：￥38710
货号：310-28-2ug	规格：2ug	目录价：￥1163
货号：310-28-500ug	规格：500ug	目录价：￥57513

产品详情

产品名称:

Recombinant Human sOX40 Ligand

别名:

TNFSF4, OX40L, Gp34, CD252

产品描述:

OX40L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX40L signals specifically through the OX40 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX40/OX40L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. OX40/OX40L signaling plays an important role in immuno-regulatory communication, enabling the immune system to distinguish between "friend vs. foe" during activation; a mechanism typically termed immuno-tolerance. Recombinant OX40L is a glycosylated 133 amino acid protein corresponding to the extracellular TNF homologous domain of the full length transmembrane protein. It migrates with an apparent molecular mass of 15.5-25.0 kDa on SDS-PAGE.

宿主来源:

Hi-5 Insect cells

推荐稀释度:

请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度

预期分子量:

15.4 kDa

产品形式:

Standard

产地:

美国

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