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折扣/货期| 货号：310-02-100ug | 规格：100ug | 目录价：￥5760 |
| 货号：310-02-10ug | 规格：10ug | 目录价：￥1163 |
| 货号：310-02-1mg | 规格：1mg | 目录价：￥25574 |
| 货号：310-02-250ug | 规格：250ug | 目录价：￥11161 |
| 货号：310-02-500ug | 规格：500ug | 目录价：￥16583 |
| 货号：310-02-50ug | 规格：50ug | 目录价：￥2900 |
产品详情
产品名称:
Recombinant Human sCD40 Ligand
别名:
soluble CD40 Ligand, TNFSF5, TRAP, CD154, Gp39, T-BAM
产品描述:
CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40 Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to "immunodeficiency with hyper-IgM", a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain. The soluble form of CD40L is an 18 kDa protein comprising the entire TNF homologous region of CD40L and is generated in vivo by an intracellular proteolytic processing of the full length CD40L. Recombinant Human soluble CD40 ligand is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
16.3 kDa
产品形式:
Standard
产地:
美国
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